Spindle cell carcinoma is very rare variant of quamous cell carcinoma. This variant
had been included in the carcinosarcoma, and also confused with pseudosarcoma. The
spin61e cell component was proved as squamous cell by electron microscopic
examination and tissue culture studs.
The authors experienced a case of spindle cell valiant of squamous cell carcinoma of
the esopha. gnus in a 67 fears old male patient. He had been suffered from dysphagia
and postprandial chest pain for five months. About ten kilogram of weight was lost
during four months prior to this entry.
An esoptagogram revealed a filling defect of barium on the mid-esophagus, suggesting
of a polyp.
Laboratory findings including hemogram, blood chemistry. urinalysis and direct smear
of sputum for acid-fast bacilli, were all within normal limits.
A segmental resection of the esophagus with esophagogastrostomy was performed.
On gross examination, there was a polypoid mass, 3.7×2.5×2.0㎝, on the esophageal
mucosa. It revealed dark brown and dirty surface with firm consistency. On cut section,
it showed tan gray to light yellow rough trabeculated cut surface.
On the microscopic examination, it was composed of spindle shaped cells with
interlacing or whorling pattern. In several areas, bi29are multinucleated tumor giant cells
were observed. Varying amount of collagen and reticulin fibers were noted. There were
intraepithelial squamous cell carcinoma near the stalk of the polyp, and islands of
squamous cells in the spindle cell component. a distinct transitional gone was observed.
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